Figure 2. Presence and distribution of CpG dinucleotides in B19V genome.
The left terminal region and the proximal part of the internal region of B19V genome are shown in the diagram (nt.1–586, scale at the top line). Upper line: thick segment, left terminal region and axis of dyad symmetry; thin segment, internal region. Middle line: distribution of CpG dinucleotides, TATA box and start of transcription. Lower line: distribution of cis- recognition sequence elements. NSBE 1–4, NS protein binding elements 1–4 [19]. Sp1/3, Sp factors 1/3 recognition sequences.