Table 1. Participant characteristics according to tHcy status.
| tHcy<15 µmol/L N = 106 | tHcy≥15 µmol/L N = 49 | Statistic | P value | |
| Demographics | ||||
| Age, mean (SD) | 65.5 (10.1) | 73.7 (7.9) | t = −5.01 | <0.001 |
| Male gender, n (%) | 54 (50.9) | 35 (71.4) | χ2 = 5.75 | 0.016 |
| Years of education, mean (SD) | 12.5 (3.1) | 11.9 (3.6) | t = 1.09 | 0.276 |
| Married, n (%) | 79 (74.5) | 37 (75.5) | χ2 = 0.00 | 0.971 |
| Lifestyle | ||||
| Ever smoked, n (%) | 55 (51.9) | 33 (67.3) | χ2 = 3.26 | 0.071 |
| Current smoker, n (%) | 3 (2.8) | 6 (12.2) | FET | 0.029 |
| Physically active, n (%) | 29 (27.4) | 10 (20.4) | χ2 = 0.86 | 0.354 |
| BMI, mean (SD) | 26.5 (4.3) | 26.8 (3.6) | t = −0.39 | 0.700 |
| Risky alcohol use, n (%) | 36 (34.0) | 12 (24.5) | χ2 = 1.41 | 0.236 |
| Clinical | ||||
| IHD, n (%) | 39 (36.8) | 17 (34.7) | χ2 = 0.06 | 0.800 |
| CHF, n (%) | 18 (17.0) | 17 (34.7) | χ2 = 6.01 | 0.014 |
| Diabetes, n (%) | 13 (12.3) | 15 (30.6) | χ2 = 7.62 | 0.006 |
| Hypertension, n (%) | 42 (39.6) | 31 (63.3) | χ2 = 7.52 | 0.006 |
| Dyslipidemia, n (%) | 58 (54.7) | 28 (57.1) | χ2 = 0.08 | 0.778 |
| Systolic BP, mean (SD) | 135.2 (19.5) | 136.2 (23.6) | t = −0.27 | 0.787 |
| Diastolic BP, mean (SD) | 81.8 (11.4) | 79.3 (12.6) | t = 1.19 | 0.236 |
| Ejection fraction, mean (SD) | 61.7 (15.5) | 56.0 (19.1) | t = 1.98 | 0.049 |
| HADSA, mean (SD)* | 3.4 (2.1) | 1.9 (2.0) | z = 3.85 | <0.001 |
| HADSD, mean (SD)* | 2.2 (1.9) | 2.2 (1.8) | z = −0.18 | 0.859 |
*
Geometric mean.
Abbreviations: tHcy – total plasma homocysteine, FET – Fisher's exact test, BMI – body mass index, IHD – ischemic heart disease, CHF – congestive heart failure, BP – blood pressure, HADSA – hospital anxiety and depression scale anxiety score, HADSD - hospital anxiety and depression scale depression score.