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. 2012 Mar 7;7(3):e32539. doi: 10.1371/journal.pone.0032539

Table 3. The competition analysis of the transmission efficiency for the transmitted/founder viruses and chronic HIV-1 isolates.

Viral pairs Variant(co-receptor) Inoculum viruses (TCID50) Transmission efficiency*
BAL and CH040 BAL (R5) 3.0×105 1.72%
CH040(R5) 1.0×106 1.68%
BAL and CH058 BAL (R5) 1.0×104 0.44%
CH058(R5) 0.6×104 0.63%

HIV-1 CH040 and CH058 are transmitted/founder viruses and HIV-1 BAL is a chronic isolate.

*The transmission efficiency was calculated by dividing the viral RNA copies in the inoculum with the viral RNA copies of the transmitted variants from the bottom wells. Real-time RT PCR with specific primers/probes set which could discriminate CH040, CH058 and BAL viruses was employed.