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. 2012 Mar 7;7(3):e32718. doi: 10.1371/journal.pone.0032718

Figure 1. CGA lowered fasting blood glucose in db/db mice and stimulated glucose transport into soleus muscle.

Figure 1

A: Oral glucose tolerance test was performed on db/db mice (n = 4) treated with different treatments. 2 g/kg glucose was loaded at 0 minute. Blood samples were collected at −10, 0, 15, 30 60 and 120 minutes for glucose measurement. Results are the mean ± SD of four mice. B: Soleus muscle was isolated from db/db mice and treated with CGA or/and 100 nmol/l insulin or 2 mmol/l metformin for 30 minutes. 2-deoxyglucose uptake was measure over a 30-minute period, using liquid scintillation counter. Results are the mean ± SE of three independent experiments. *P<0.05, **P<0.01 compared with controls. DC = Diabetic Control.