Table 1. Baseline characteristics of study participants comparing individuals with and without HIV-associated dementia.
Overall (n = 30) | No dementia (n = 24) | HIV-associated dementia (n = 6) | |
Demographic Characteristics | |||
Age [mean (SD)] | 39 (10) | 47 (6.8) | 37 (10) |
Male [% (n)] | 57% (17) | 50% (12) | 83% (5) |
Marital Status [% (n)] | |||
Never Married | 13% (4) | 17% (4) | 0% |
Married | 63% (19) | 54% (13) | 83% (5) |
Widowed | 20% (6) | 21% (5) | 17% (1) |
Divorced/separated | 4% (1) | 4% (1) | 0% |
Highest level of education achieved [% (n)] | |||
Less than primary | 23% (7) | 21% (5) | 33% (2) |
At least primary | 27% (8) | 29% (7) | 17% (1) |
Secondary | 37% (11) | 42% (10) | 17% (1) |
More than secondary | 14% (4) | 12% (2) | 33% (2) |
Socio-economic status | |||
Electricity in dwelling [% (n)] | 37% (11) | 38% (9) | 33% (2) |
Running water in dwelling [% (n)] | 13% (4) | 13% (3) | 17% (1) |
Selected clinical characteristics | |||
WHO Stage currently [% (n)] | |||
Stage 1 | 13% (4) | 13% (3) | 17% (1) |
Stage 2 | 27% (8) | 29% (7) | 17% (1) |
Stage 3 | 37% (11) | 33% (8) | 50% (3) |
Stage 4 | 23% (7) | 25% (6) | 17 (1) |
Nadir CD4 cell count [mean (SD)] | 198 (150) | 215 (157) | 127 (103) |
Current CD4 cell count [mean (SD)] | 323 (211) | 337 (227) | 268 (134) |
Moderate to severe depression [%(n)] * | 23% (7) | 21% (5) | 33% (2) |
Functional Status Measures | |||
Karnovsky Performance Scale [mean (SD)]Range (0–100) | 92 (20) | 92 (22) | 91 (4.1) |
Activities of Daily Living (ADL)[mean (SD)] Range (0–4) | 4 (0) | 4 (0) | 4 (0) |
Independent ADL [mean (SD)] Range (0–8) | 7.8 (0.7) | 7.8 (0.7) | 8 (0) |
Physical Function[mean (SD)] Range (0–100) | 89(19) | 97 (4) | 87 (201) |
Role Limitation due to Physical Function [mean (SD)] Range (0–100) | 82 (5.1) | 80 (31) | 89 (16) |
Patient assessment of own functioning inventory (PAOFI)† [mean (SD)] Range (0–165) | 12 (14) | 13 (15) | 12 (5.9) |
Score ≥10 on Patient Health Questionnaire (PHQ9);
PAOFI- a score of 0 reflects no impairment.