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. Author manuscript; available in PMC: 2013 Jan 1.
Published in final edited form as: Anesthesiology. 2012 Jan;116(1):205–215. doi: 10.1097/ALN.0b013e31823db712

Table 4.

Summary of Anesthesia Implications

Preoperative factors

Patients orthostatic hypotension with or without supine hypertension
Be aware of gastroparesis and aspiration risk
Be aware of blood volume status for the conduct of anesthesia
Be aware of slight anemia due to reduced erythropoiesis
Consider holding oral vasopressors to prevent drug interactions intraoperatively

Intraoperative factors

General versus regional anesthesia choice would be dependent on procedure type
Patients require adequate monitoring and constant vigilance
Hypothermia and hyperthermia are both risks with poor thermal regulation
Intubation may require rapid sequence with cricoid pressure
Patient positioning may have significant effects on vital signs
Nitroglycerine, prone positioning or reverse trendelenberg can be used for supine hypertension
Sudden blood volume changes may precipitate untoward blood pressure response (rapid infusions or rapid
blood loss)
Pneumoperitoneum should be applied with extreme caution or avoided if possible
Vasopressors and Inotropes can have resistance or undue sensitivity (See Table 3.)
Abnormal electrolyte values affect responses to medications

Postoperative factors

Anticipate volume changes in the postoperative period and observe with a higher level of care
Orthostatic hypotension requires good blood volume and assistance with first ambulation
Abnormal electrolyte values affect responses to medications
Thermal regulation may be an issue in the recovery period
Ileus can be worsened by opiate use in the postoperative period
Restart home dysautonomia medications before discharge