Table 1.

(A) Pearson correlations for mRNA expression values measured in 288 LCLs. The “top half” of the table contains nominal p-values as well as Bonferroni adjusted p-values in parentheses, while the “bottom half” lists r values. Shaded and bolded values represent significant correlations (nominal p-value<0.05). (B) Spearman correlations, nominal p-values and Bonferroni adjusted p-values as shown in (A) for protein concentrations measured in 268 human hepatic biopsy samples

(A) Human LCL mRNA expression correlations.
	SHMT1	SHMT2	COMT	MAT2A	MAT2B
SHMT1	------------	2.32E-12	2.97E-04	5.02E-11	1.22E-06
		(2.78E-11)	(3.56E-03)	(6.02E-10)	(1.46E-05)
SHMT2	0.40	------------	3.20E-11	7.05E-04	0.125
			(3.84E-10)	(8.46E-03)
COMT	0.21	0.38	------------	2.52E-03	0.137
				(3.02E-02)
MAT2A	0.38	0.20	0.18	------------	5.16E-05
					(6.19E-04)
MAT2B	-0.28	−0.09	−0.09	0.24	------------

(B) Human hepatic biopsy cytosol protein expression correlations.
	SHMT1	BHMT	COMT
SHMT1	-------------	0.018	0.003
		(0.216)	(0.036)
BHMT	0.15	-------------	0.003
			(0.036)
COMT	0.18	0.18	-------------