Table 5.
Blood data before and after G-CSF administration
| Group | Baseline | After G-CSF administration | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 day | 2 days | 3 days | 4 days | 5 days | 6 days | 7 days | 14 days | 1 month | 6 months | ||
| 5 μg | |||||||||||
| WBC (×103/mm3) | 7.2 ± 1.6 | 26.7* ± 10.7 | 25.0* ± 5.5 | 24.9* ± 6.6 | 23.3* ± 9.3 | 20.8* ± 9.6 | 10.4 ± 3.2 | 8.2 ± 2.4 | 8.2 ± 2.4 | 7.3 ± 2.8 | 7.2 ± 0.4 |
| Neutrophils (×103/mm3) | 4.5 ± 1.5 | 22.1* ± 9.2 | 20.9* ± 5.8 | 20.6* ± 6.1 | 19.0* ± 7.7 | 151.9* ± 7.7 | 6.8 ± 2.8 | 5.1 ± 2.0 | 5.9 ± 2.4 | 4.7 ± 2.3 | 4.1 ± 0.1 |
| CRP (mg/dl) | 0.7 ± 1.2 | 0.8 ± 1.3 | 0.8 ± 1.3 | 0.8 ± 1.1 | 0.8 ± 1.0 | 0.7 ± 1.0 | 0.7 ± 1.0 | 0.8 ± 0.9 | 4.6*,a ± 6.9 | 2.9*,a ± 6.1 | 0.2 ± 0.2 |
| 10 μg | |||||||||||
| WBC (×103/mm3) | 6.1 ± 1.6 | 29.3* ± 4.8 | 31.5* ± 5.6 | 35.2* ± 7.2 | 27.8* ± 9.3 | 25.1* ± 8.0 | 10.5 ± 2.8 | 6.7 ± 1.6 | 4.8 ± 1.9 | 6.0 ± 1.9 | 6.8 ± 2.1 |
| Neutrophils (×103/mm3) | 3.5 ± 1.1 | 25.4* ± 4.2 | 25.1* ± 8.8 | 29.8* ± 6.2 | 22.4* ± 7.7 | 20.0* ± 6.5 | 6.6 ± 2.2 | 3.9 ± 1.2 | 2.8 ± 1.4 | 3.4 ± 1.2 | 4.0 ± 1.6 |
| CRP (mg/dl) | 0.3 ± 0.8 | 0.6 ± 1.3 | 1.1 ± 2.6 | 1.6 ± 3.4 | 1.4 ± 2.4 | 1.8 ± 2.9 | 2.0 ± 4.3 | 1.7 ± 3.3 | 0.7 ± 1.2 | 0.4 ± 0.5 | 0.1 ± 0.1 |
* p < 0.05 compared with the baseline level
aIncrease due to the surgical site infection of case 4