Table 6.
Author [ref.] | Sample size | Clinical scenario | G-CSF dose (μg/kg/day) | Route of administration | Duration of G-CSF therapy (days) | Peak WBC count (×103/μl) |
---|---|---|---|---|---|---|
Engelmann et al. [2] | 23 | AMI | 10 | s.c. | 5 | 42.9 ± 25.7 |
Ince et al. [5] | 15 | AMI | 10 | s.c. | 6 | 55 ± 8 |
Nefussy et al. [12] | 19 | ALS | 5 | s.c. | 4 | 30.0 ± 7.2 |
Ripa et al. [15] | 39 | AMI | 10 | s.c. | 6 | 51 ± 8 |
Shyu et al. [21] | 7 | CI | 15 | s.c. | 5 | 42.9 ± 9.6 |
Takano et al. [22] | 18 | AMI | 2.5 | s.c. | 5 | 29.4 ± 9 |
Valgimigli et al. [23] | 10 | AMI | 5 | s.c. | 4 | 35 ± 11 |
Zohlnhofer et al. [27] | 56 | AMI | 10 | s.c. | 5 | 48 ± 15 |
Our cases | 5 | Myelopathy | 5 | i.v. | 5 | 26.7 ± 10.7 |
10 | Myelopathy | 10 | i.v. | 5 | 35.2 ± 7.2 |
CI cerebral infarction, AMI acute myocardial infarction, ALS amyotrophic lateral sclerosis, s.c. subcutaneous injection, i.v. intravenous injection