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. Author manuscript; available in PMC: 2013 Mar 1.
Published in final edited form as: J Neurochem. 2012 Feb 9;120(6):948–963. doi: 10.1111/j.1471-4159.2011.07630.x

Figure 5. Microglial morphology and number are significantly affected by sex at postnatal day 30 within many brain regions analyzed.

Figure 5

At P30, analysis of microglial morphology revealed a significant effect of morphology within all brain regions, as all brain regions had significantly more microglia with thicker, longer or thinner/ramified processes than microglia with stout processes or amoeboid morphology. Within the parietal cortex, CA3 and dentate gyrus of the hippocampus, and within the amygdala females had significantly more microglia with a more activated morphology (thick, long processes) than males (within-subjects ANOVA, *p < 0.05 compared to males within the same morphology; n = 4 rats/group). The CA1 of the hippocampus and the paraventricular nucleus do not exhibit a sex difference in microglial morphology at this age. Data represent the mean ± SEM of all Iba1+ cells in each morphological category across all sections analyzed.