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. Author manuscript; available in PMC: 2013 Aug 1.
Published in final edited form as: J Cell Physiol. 2012 Aug;227(8):3119–3127. doi: 10.1002/jcp.23065

Figure 4. Effect of reduced level of CXCL5/LIX in CM on pro-survival signal transduction pathways in neurons.

Figure 4

A. Western blot analysis of total lysates prepared from rat cortical neurons treated with: 1. neuronal CM; 2. CG4-Ol CM; 3. CG4-Ol GFP CM; 4. CG4-Ol GFP-Agno CM; 5. CG4-Ol GFP CM + neutralizing anti-LIX antibodies (3 µg/ml); 6. 1h pretreatment with rLIX (100 ng/ml) + CG4-Ol GFP-Agno CM; 7. CG4-Ol GFP CM + IgG1 (3 µg/ml); 8. CG4-Ol GFP-Agno CM + BSA (100 ng/ml). B. Effect of SB 202190 on p38 MAPK, activation of caspase 3 and apoptotic signaling in neurons treated with CM from agnoprotein-expressing cells.