Table 1. Patient characteristics at each clinical assessment.
| Baseline | 6-Months | 18-Months | ||||
|---|---|---|---|---|---|---|
| Mean | (SD) | Mean | (SD) | Mean | (SD) | |
| Demographics | ||||||
| Age | 65.9 | (10.6) | 66.4 | (10.5) | 67.3 | (10.6) |
| Education | 14.9 | (3.0) | ||||
| Sex (% Male) | 66.0 | |||||
| PD Duration (years) | 8.2 | (6.1) | ||||
| Mood | ||||||
| AS | 13.0 | (6.9) | 12.9 | (6.8) | 14.0 | (7.3) |
| % with AS ≥ 14 | 43.0 | - | 43.0 | - | 52.5 | - |
| BDI | 9.4 | (7.0) | 8.6 | (6.3) | 9.5 | (6.2) |
| % with BDI ≥ 15 | 17.6 | - | 17.1 | - | 20.3 | - |
| % on an antidepressant | 31.5 | - | 32.4 | - | 34.1 | - |
| Motor | ||||||
| LEDa | 617.5 | (376.4) | 776.1 | (580.8) | 803.6 | (623.4) |
| UPDRS on | 28.6 | (10.8) | 28.6 | (10.5) | 30.7 | (11.5) |
| UPDRS off | 34.3 | (12.9) | ||||
a
LED data only available for 90 patients
Note. PD=Parkinson's disease; AS=Apathy Scale; BDI=Beck Depression Inventory; LED=Levodopa equivalent dose; UPDRS=Unified Parkinson's Disease Rating Scale (motor portion)