. Author manuscript; available in PMC: 2013 Mar 1.

Published in final edited form as: J Cardiovasc Pharmacol. 2012 Mar;59(3):281–287. doi: 10.1097/FJC.0b013e31823fc3f5

TABLE 1.

Body weight (BW), blood glucose (BG), 24-h urine volume (UV), kidney masses indexes (KMI), and systolic blood pressure (SBP) of sham and diabetic rats at the end of study.

Variable	Sham	DIABETES
Variable	Sham	Vehicle	ALISK	HCTZ	AMLO	HCTZ+AMLO	ALISK+HCTZ	ALISK+AMLO	ALISK+HCTZ+AMLO
BW (g)	480±11	300±20*	297±11*	304±10*	311±13*	285±5*	315±14*	293±11*	287±10*
BG (mg/dl)	88±3	499±29*	473±30*	488±12*	488±19*	519±24*	490±21*	459±25*	445±18*
UV (ml/d)	24±3	205±16*	183±10*	199±14*	184±9*	168±10*	180±17*	175±10*	188±8*
KMI (mg/g)	6.3±0.1	11.4±0.6*	11.3±0.4*	11.1±0.4*	11.2±0.4*	11.8±0.6*	10.3±0.3*	10.2±0.3*	10.2±0.4*
SBP (mmHg)	112±1	114±1	113±2	112±1	112±1	112±1	113±1	112±1	114±1

ALISK = aliskiren; HCTZ = hydrochlorothiazide; AMLO = amlodipine. Data are mean ± SEM. P < 0.05 vs. sham.