Table 4.
All histologies |
Squamous cell cancer |
Small cell lung cancer |
Adenocarcinoma |
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---|---|---|---|---|---|---|---|---|---|---|
Years | Controls | Cases | ORa (95% CI) | Cases | ORa (95% CI) | Cases | ORa (95% CI) | Cases | ORa (95% CI) | |
Men | Never smokers | 2883 | 220 | 1.0 | 51 | 1.0 | 22 | 1.0 | 99 | 1.0 |
> 35 | 716 | 170 | 2.2 (1.8-2.8) | 71 | 4.3 (3.0-6.3) | 21 | 3.5 (1.9-6.5) | 59 | 2.2 (1.6-3.1) | |
26-35 | 1073 | 306 | 2.9 (2.4-3.5) | 121 | 5.5 (3.9-7.7) | 36 | 3.7 (2.2-6.4) | 97 | 2.5 (1.8-3.3) | |
16-25 | 1613 | 779 | 5.1 (4.3-6.0) | 312 | 9.5 (7.0-13.0) | 94 | 6.7 (4.1-10.7) | 233 | 3.9 (3.1-5.0) | |
11-15 | 833 | 579 | 7.8 (6.5-9.4) | 255 | 15.7 (11.5-21.5) | 70 | 11.0 (6.7-17.9) | 150 | 5.2 (4.0-6.9) | |
6-10 | 797 | 737 | 10.8 (9.0-12.8) | 381 | 24.8 (18.2-33.8) | 85 | 13.5 (8.4-21.8) | 145 | 5.3 (4.1-7.0) | |
2-5 | 615 | 925 | 18.3 (15.3-21.8) | 445 | 38.8 (28.5-52.8) | 154 | 31.6 (20.0-50.0) | 178 | 8.4 (6.4-10.9) | |
Current smokers | 3829 | 6784 | 23.6 (20.4-27.2) | 3038 | 45.6 (34.3-60.6) | 1249 | 45.7 (29.9-70.0) | 1398 | 10.8 (8.7-13.3) | |
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Women | Never smokers | 1902 | 609 | 1.0 | 96 | 1.0 | 50 | 1.0 | 343 | 1.0 |
> 35 | 61 | 22 | 1.3 (0.7-2.1) | 5 | 1.8 (0.7-4.7) | 1 | 0.9 (0.1-6.0) | 13 | 1.3 (0.7-2.4) | |
26-35 | 95 | 24 | 1.0 (0.6-1.6) | 6 | 1.6 (0.7-3.8) | 3 | 1.5 (0.5-5.1) | 10 | 0.7 (0.3-1.3) | |
16-25 | 189 | 94 | 2.0 (1.5-2.6) | 22 | 3.0 (1.8-5.0) | 9 | 2.0 (1.0-4.3) | 44 | 1.4 (1.0-2.0) | |
11-15 | 93 | 73 | 3.3 (2.4-4.6) | 18 | 5.4 (3.1-9.6) | 6 | 3.0 (1.2-7.2) | 36 | 2.4 (1.6-3.6) | |
6-10 | 110 | 106 | 4.0 (3.0-5.4) | 36 | 8.5 (5.4-13.3) | 12 | 5.3 (2.7-10.3) | 39 | 2.3 (1.5-3.3) | |
2-5 | 109 | 166 | 6.7 (5.1-8.9) | 37 | 9.4 (6.0-14.7) | 29 | 12.0 (7.1-20.1) | 66 | 3.9 (2.8-5.5) | |
Current smokers | 691 | 1423 | 7.8 (6.8-9.0) | 343 | 13.6 (10.5-17.7) | 331 | 21.7 (15.5-30.1) | 462 | 4.2 (3.5-5.0) |
Odds ratio (OR) estimated with logistic regression, conditional on study center, adjusted for age and smoking of other types of tobacco