TABLE 1.
Strains and plasmids | Genotypes/Remarks | Sources and references |
---|---|---|
A. actinomycetemcomitans | ||
VT1169 | a Rifr, Nalr derivative of SUNY465, serotype b | (Mintz, 2004) |
VT1169/pKM2/ltxP | VT1169 transformed with plasmid pKM2/ltxP, which is referred as the “wild type” | This study |
aae mutant (aae::Kan) | An isogenic aae (epithelial adhesin) mutant of SUNY465 | (Rose et al., 2003) |
rmlC (rmlC::pLOF/Sp) | Rhamnose mutant, transposon pLOF/Sp inserted into rmlC(TDP-4-keto-6-deoxy-D-glucose 3, 5-epimerase) | (Tang & Mintz, 2010) |
rmlC/pKM2/ltxP | rmlC mutant transformed with pKM2/ltxP | This study |
rmlC /rmlC+ | rmlC mutant complemented with plasmid pKM2/ltxP/rmlC | (Tang & Mintz, 2010 |
rmlC /tolC+ | rmlC mutant transformed with plasmid pKM2/ltxP/tolC to over-express TolC | This study |
Plasmids | ||
pLOF/Sp | Tn10-based transposon vector; Apr, Spr | (Mintz, 2004) |
pKM2 | A plasmid containing chloramphenicol acetyltransferase, which can be transformed into serotype b A. actinomycetemcomitans , Cmr | (Gallant et al., 2008) |
pKM2/ltxP | pKM2 containing ~500-bp ltx_promoter, Cmr | (Tang & Mintz, 2010) |
pKM2/ltxP/rmlC | pKM2 containing ~500-bp ltx promoter + rmlC sequence, Cmr | (Tang & Mintz, 2010) |
pKM2/ltxP/tolC | pKM2 containing ~500-bp ltx promoter + tolC sequence, Cmr | This study |
Ap: ampicillin; Cm: chloramphenicol; Nal: nalidixic acid; Rif: rifampicin; Sp: spectinomycin