Table 1.
Distribution of TBX21 -1993T/C allelic frequencies in cases and controls n (%)
| Variables | Case | Control | Adjusted OR (95% CI) | P trend |
| Age (yr) (mean ± SD) | 41.14 ± 7.10 | 41.69 ± 8.83 | 0.8841 | |
| Gender | ||||
| Male | 124 (56.36) | 143 (54.58) | 0.6952 | |
| Female | 96 (43.64) | 119 (45.42) | ||
| Smoking status | ||||
| Never | 160 (72.73) | 201 (76.72) | 0.3142 | |
| Always | 60 (27.27) | 61 (23.28) | ||
| Drinking status | ||||
| Never | 149 (67.73) | 188 (71.76) | 0.3372 | |
| Always | 71 (32.27) | 74 (28.24) | ||
| Family history of cancer | ||||
| No | 181 (82.27) | 240 (91.60) | 0.0022 | |
| Yes | 39 (17.73) | 22 (8.40) | ||
| TBX21 -1993 | ||||
| T | 356 (80.91) | 473 (90.27) | 1.00 | - |
| C | 84 (19.09) | 51 (9.73) | 2.06 (1.44-2.96) | < 0.0012 |
| T/T | 154 (70.00) | 219 (83.59) | 1.00 | - |
| T/C | 48 (21.82) | 35 (13.36) | 1.84 (1.13-3.01) | 0.0153 |
| C/C | 18 (8.18) | 8 (3.05) | 3.42 (1.41-8.31) | 0.0073 |
1
Mann-Whitney U test;
2
χ2 test;
3
Multivariate unconditional logistic regression model. SD: Standard deviation; CI: Confidence interval; OR: Odds ratio.