Table 1.
Demographic, anthropometric, clinical, and histological data in patients with chronic HCV infection.
| Metabolic syndrome | ||||
| Yes (n = 27) | No (n = 98) | Total | p-value*) | |
| n (%) | n (%) | n | ||
| Sex | ||||
| Male | 12 (44.4) | 66 (67.3) | 78 | 0.043 |
| Female | 15 (55.6) | 32 (32.7) | 47 | |
| Age | ||||
| <60 | 19 (70.4) | 69 (70.4) | 88 | 1.000 |
| ≥60 | 8 (29.6) | 29 (29.6) | 37 | |
| Antiviral treatment status | ||||
| Naive | 9 (33.3) | 42 (42.9) | 51 | 0.507 |
| Nonresponders/relapsers | 18 (66.7) | 56 (57.1) | 74 | |
| Stage of fibrosis on liver biopsy | ||||
| F0-F2 | 13 (56.5) | 47 (61.0) | 60 | 0.809 |
| F3-F4 | 10 (43.5) | 30 (39.0) | 40 | |
| Hepatic steatosis detected by abdominal ultrasound | ||||
| No | 10 (52.6) | 53 (67.9) | 63 | 0.283 |
| Yes | 9 (47.4) | 25 (32.1) | 34 | |
| Systemic arterial hypertension | ||||
| No | 11 (40.7) | 76 (77.6) | 87 | <0.001 |
| Yes | 16 (59.3) | 22 (22.4) | 38 | |
| HOMA-IR | ||||
| <3.0 | 6 (22.2) | 73 (74.5) | 79 | <0.001 |
| ≥3.0 | 21 (77.8) | 25 (25.5) | 46 | |
| Body mass index | ||||
| <25 kg/m2 | 4 (14.8) | 65 (66.3) | 69 | <0.001 |
| 25–30.0 kg/m2 | 23 (85.2) | 33 (33.7) | 56 | |
| Waist circumferencea) | ||||
| Adequate | 14 (51.9) | 89 (90.8) | 103 | <0.001 |
| Elevated | 13 (48.1) | 9 (9.2) | 22 | |
| Waist:hip ratiob) | ||||
| Adequate | 1 (3.7) | 39 (39.8) | 40 | <0.001 |
| Elevated | 26 (92.3) | 59 (60.2) | 85 | |
| Body fat percentagec) | ||||
| Adequate | 4 (14.8) | 58 (59.2) | 62 | <0.001 |
| Elevated | 23 (85.2) | 40 (40.8) | 63 | |
*
Fisher's exact test.
a
Adequate WC: ≤88 cm for women and ≤102 cm for men.
b
Adequate WHR: ≤85 cm for women and ≤90 cm for men.
c
Adequate BF%: <32 cm for women and <25 cm for men.