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. Author manuscript; available in PMC: 2012 Mar 8.
Published in final edited form as: Ann Thorac Surg. 2010 Dec;90(6):1985–1995. doi: 10.1016/j.athoracsur.2010.08.005

Table 4.

Predictors of Neurodevelopmental Outcomes

Predictor Cognition
Language
Fine-Motor
Visual-Motor
Executive Function
Inattention
Impulsivity
Social Skills
Coefficient p Value Coefficient p Value Coefficient p Value Coefficient p Value Coefficient p Value Coefficient p Value Coefficient p Value Coefficient p Value
Confirmed genetic anomaly −20.20 <0.001 −18.73 <0.001 −17.69 <0.001 −11.17 <0.001 −15.06 <0.001 −5.63 0.019
SES 3.56 0.003 5.38 <0.001 3.31 0.001 4.48 <0.001 −1.03 0.001 1.93 0.005
Maternal education 4.46 0.004
Gestational age 1.21 0.12 1.83 <0.001 1.15 0.016
White 4.67 0.003 3.56 <0.001
African American −7.69 0.001
Birth weight 3.54 0.042 −1.65 0.001 −1.19 0.024 4.25 0.002
Single-ventricle CHD 1.03 0.021
Male sex −5.11 0.004 1.38 0.04
Preoperative mechanical ventilation −4.45 0.024
APOE ε4 allele 5.52 0.007 5.04 0.01
Additional operations with CPB −6.50 0.001 −5.35 0.03

APOE = apolipoprotein E; CHD = congenital heart defect; CPB = cardiopulmonary bypass; SES = socioeconomic status.