Table 1.
Key characteristics of pharmacokinetic treatments for drug addiction.
Characteristic | Peripheral blocker (antibody) | Increased drug metabolism | ||
---|---|---|---|---|
Active immunity | Passive immunity | Enzyme | Catalytic antibody | |
Onset of action | Weeks to months | Immediate | Immediate | Immediate |
Duration of action | Months | Days | Days | Days |
Specificity of action | Very high | Very high | High | Very high |
Control over treatment agent | Low | High | High | High |
Possibility of saturating binding sites | Medium | Medium | Low | Low |
Likely clinical use | Addiction | Toxicity/overdose | Toxicity/overdose | Toxicity/overdose |