TABLE 1.
DEMOGRAPHICS AND BMI OF SUBSPECIALTY PULMONARY EVALUATION COHORT
| Study Subcohort |
Subcohort Biomarkers Available* |
||||||
| Baseline Never-smokers | Cases FEV1 Less Than LLN | Control Subjects FEV1 Greater Than or Equal to LLN | Cases Less Than LLN | Control Subjects Greater Than or Equal to LLN | P Value† | ||
| N | 801 | 109 | 218 | 71 | 166 | ||
| WTC arrival time, n (%)‡ | Morning of 9/11 | 197 (25) | 30 (28) | 49 (22) | 15 (21) | 32 (19) | 0.108 |
| Afternoon of 9/11 | 498 (62) | 57 (52) | 148 (68) | 42 (59) | 117 (71) | ||
| Anytime on 9/12 | 106 (13) | 22 (10) | 21 (10) | 14 (20) | 17 (10) | ||
| 9/11 to evaluation, mo§ | MME | 2.7 (2–4) | 2.6 (2.1–4) | 2.7 (2.1–3.8) | 2.7 (2.3–3.8) | 2.7 (2.1–3.3) | 0.51 |
| SPE | 33.8 (25–57) | 32.5 (23–55) | 33.5 (25–54) | 34.3 (23.5–56.4) | 33.1 (26.2–54.1) | 0.81 | |
| BMI, kg/m2§ | MME | 28 (26–30) | 29 (27–31) | 27.6 (26–30) | 29 (26.6–31.2) | 27.6 (25.8–30.1) | 0.04 |
| SPE | 28.9 (27–31) | 30 (28–33) | 28.4 (26–31) | 29.4 (27.5–32.8) | 28.3 (26.3–30.7) | 0.005 | |
| Years of service at 9/11§ | 18.4 (11–23) | 18 (14–22) | 18.7 (11–24) | 18.3 (13.3–22.2) | 16.7 (10.5–22.5) | 0.60 | |
| Age at 9/11§ | 40 (36–45) | 40 (35–45) | 42 (37–46) | 39 (35 –45) | 42 (37–46) | 0.15 | |
| Race‡ | White | 782 (98) | 105 (96) | 210 (96) | 67 (94) | 161 (97) | 0.46 |
| African American | 19 (2) | 4 (4) | 8 (4) | 4 (6) | 5 (3) | ||
Definition of abbreviations: BMI = body mass index; LLN = lower limit of normal as defined by NHANES III; NHANES = National Health and Nutrition Examination Survey; MME = medical monitoring entry; SPE = subspecialty pulmonary examination; WTC = World Trade Center.
*
Available serum biomarkers and all measures of metabolic syndrome.
†
Data compared between cases and control subjects in subcohort with biomarkers available; P values determined by Mann-Whitney and Pearson chi-square as appropriate.
‡
Values expressed as n (%).
§
Values expressed as medians (interquartile range).