TABLE 4.

PROPORTION OF INDIVIDUALS THAT MEET EACH OF THE CRITERIA AT MEDICAL MONITORING ENTRY

Biomarker	Cases* FEV1 Less Than LLN	Control Subjects* FEV1 Greater Than or Equal to LLN	P Value†
Metabolic syndrome‡	0.27 (19/71)	0.16 (26/166)	0.07
Triglycerides ≥150 mg/dl	0.51 (36/71)	0.46 (76/166)	0.57
HDL<40 mg/dl	0.32 (23/71)	0.20 (33/166)	0.05
HDL<40 and triglycerides ≥150 mg/dl	0.28 (20/71)	0.14 (23/166)	0.006
Glucose ≥100 mg/dl	0.28 (20/71)	0.16 (26/166)	0.03
Heart rate ≥66 bpm	0.65 (46/71)	0.48 (79/166)	0.02
BMI ≥30 kg/m2	0.32 (23/71)	0.26 (43/166)	0.34
Leptin ≥10,300 pg/ml§	0.42 (30/71)	0.21 (34/166)	0.001
Pancreatic polypeptide ≤89 pg/ml‖	0.38 (27/71)	0.24 (40/166)	0.04
Amylin ≥116 pg/ml§	0.07 (5/71)	0.31 (51/166)	≤0.0001

Definition of abbreviations: BMI = body mass index; HDL = high-density lipoprotein; LLN = lower limit of normal as defined by NHANES III; NHANES = National Health and Nutrition Examination Survey.

^*Proportions in group (n in group/total).

^†P value determined by Pearson chi-square.

^‡National Heart Lung and Blood Institute/American Heart Association Criteria.

^§Values were represented as top quartiles.

^‖Values were represented as bottom quartiles.