TABLE 8.
Quantitative TST Result |
Quantitative QFT-GIT Result |
Quantitative T-Spot Result |
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Risk Stratification† | N | 0–4 mm | 5–9 mm | 10–14 mm | ≥15 mm‡ | <0.35 | 0.35–0.99 | ≥1§ | ≤4 Spots | 5–7 Spots | ≥8 Spots|| |
High risk (5-mm criteria) | 21 | 18 (85.7%) | 1 (4.8%) | 1 (4.8%) | 1 (4.8%) | 18 (85.7%) | 2 (9.5%) | 1 (4.8%) | 20 (95.2%) | 0 | 1 (4.8%) |
Moderate risk (10-mm criteria) | 409 | 362 (88.5%) | 10 (2.4%) | 21 (5.1%) | 16 (3.9%) | 392 (95.8%) | 7 (1.7%) | 10 (2.4%) | 391 (95.6%) | 3 (0.7%) | 15 (3.7%) |
Low risk (15-mm criteria) | 1,373 | 1,332 (97%) | 21 (1.5%) | 10 (0.7%) | 10 (0.7%) | 1,356 (98.8%) | 13 (1%) | 4 (0.3%) | 1,336 (97.3%) | 19 (1.4%) | 18 (1.3%) |
Definition of abbreviations: QFT-GIT = QuantiFERON-TB Gold In-Tube test; T-Spot = T-SPOT.TB test; TST = tuberculin skin test.
Note: The 22 borderline T-Spot results were added into this analysis to have results for the five to seven spots category.
Risk stratification as per Centers for Disease Control and Prevention risk stratified index (30).
χ2 (trend) for 15 mm compared with the other groups = 24.6; P < 0.0001.
χ2 (trend) for 1 compared with the other groups = 24.4; P < 0.0001.
χ2 (trend) for 8 spots compared with the other groups = 11.5; P = 0.0007.