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. 2012 Feb 15;185(4):427–434. doi: 10.1164/rccm.201107-1244OC

TABLE 8.

RISK STRATIFICATION OF TUBERCULOSIS EXPOSURE BY QUANTITATIVE RESULT OF TST, QFT-GIT, AND T-SPOT*

Quantitative TST Result
Quantitative QFT-GIT Result
Quantitative T-Spot Result
Risk Stratification N 0–4 mm 5–9 mm 10–14 mm ≥15 mm <0.35 0.35–0.99 ≥1§ ≤4 Spots 5–7 Spots ≥8 Spots||
High risk (5-mm criteria) 21 18 (85.7%) 1 (4.8%) 1 (4.8%) 1 (4.8%) 18 (85.7%) 2 (9.5%) 1 (4.8%) 20 (95.2%) 0 1 (4.8%)
Moderate risk (10-mm criteria) 409 362 (88.5%) 10 (2.4%) 21 (5.1%) 16 (3.9%) 392 (95.8%) 7 (1.7%) 10 (2.4%) 391 (95.6%) 3 (0.7%) 15 (3.7%)
Low risk (15-mm criteria) 1,373 1,332 (97%) 21 (1.5%) 10 (0.7%) 10 (0.7%) 1,356 (98.8%) 13 (1%) 4 (0.3%) 1,336 (97.3%) 19 (1.4%) 18 (1.3%)

Definition of abbreviations: QFT-GIT = QuantiFERON-TB Gold In-Tube test; T-Spot = T-SPOT.TB test; TST = tuberculin skin test.

*

Note: The 22 borderline T-Spot results were added into this analysis to have results for the five to seven spots category.

Risk stratification as per Centers for Disease Control and Prevention risk stratified index (30).

χ2 (trend) for 15 mm compared with the other groups = 24.6; P < 0.0001.

§

χ2 (trend) for 1 compared with the other groups = 24.4; P < 0.0001.

||

χ2 (trend) for 8 spots compared with the other groups = 11.5; P = 0.0007.