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. 2012 Feb 15;185(4):427–434. doi: 10.1164/rccm.201107-1244OC

TABLE 9.

RISK STRATIFICATION OF TUBERCULOSIS EXPOSURE BY TEST AGREEMENT*

Test Results N High Risk (5-mm criteria) Moderate Risk (10-mm criteria) Low Risk (15-mm criteria)
All tests negative 1,693 16 (1%) 359 (21.2%) 1,318 (77.9%)
One test positive 68 4 (5.9%) 33 (48.5%) 31 (45.6%)
 TST only 32 2 (6.3%) 23 (71.9%) 7 (21.9%)
 QFT-GIT only 21 2 (9.5%) 8 (38.1%) 11 (52.4%)
 T-Spot only 15 0 (0%) 2 (13.3%) 13 (86.7%)
Two tests positive 10 0 (0%) 7 (70%) 3 (30%)
 TST and QFT-GIT 1 0 (0%) 1 (100%) 0 (0%)
 TST and T-Spot 5 0 (0%) 5 (100%) 0 (0%)
 QFT-GIT and T-Spot 4 0 (0%) 1 (25%) 3 (75%)
All three tests positive 10 1 (10%) 7 (70%) 2 (20%)

Definition of abbreviations: QFT-GIT = QuantiFERON-TB Gold In-Tube test; T-Spot = T-SPOT.TB test; TST = tuberculin skin test.

*

Risk stratification as per Centers for Disease Control and Prevention risk stratified index (30).

χ2 (trend) for low risk compared with the other groups = 61.6; P < 0.0001.