Table 1.
Collection of homologous proteins of T3SS from various species. OM, outer membrane; IM, inner membrane.
| localization |
Salmonella |
Shigella |
Yersinia |
E. coli (EHEC O157:H7) |
functional component | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| protein | amino acid | accession number | protein | amino acid | accession number | protein | amino acid | accession number | protein | amino acid | accession number | ||
| host cell membrane | SipB | 593 | AAL21765.1 | IpaB | 580 | ADA76866.1 | YopB | 401 | CAL10037.1 | EspD | 374 | ACG59617.1 | translocon |
| SipC | 409 | AAL21764.1 | IpaC | 363 | ADA76865.1 | YopD | 306 | CAL10036.1 | EspB | 312 | ACG59616.1 | translocon | |
| extracellular | SipD | 343 | AAL21763.1 | IpaD | 332 | ADA76864.1 | LcrV | 324 | CAL10039.1 | EspA | 192 | ACG59618.1 | needle tip |
| PrgI | 80 | AAL21753.1 | MxiH | 83 | ADA76875.1 | YscF | 87 | CAL10063.1 | EscF | 73 | ACG59614.1 | needle filament | |
| OM/periplasm | InvG | 562 | AAL21778.1 | MxiD | 566 | ADA76883.1 | YscC | 607 | CAL10060.1 | EscC | 512 | ACG59637.1 | secretin/outer ring |
| PrgJ | 101 | AAL21752.1 | MxiI | 97 | ADA76876.1 | YscI | 115 | CAL10066.1 | EscI | 142 | ACT74408.1 | inner rod protein | |
| InvH | 147 | AAL21780.1 | MxiM | 142 | ADA76881.1 | YscW | 131 | CAL10056.1 | assists in secretin insertion into OM | ||||
| IM | PrgK | 252 | AAL21751.1 | MxiJ | 241 | ADA76877.1 | YscJ | 244 | CAL10067.1 | EscJ | 190 | ACG59635.1 | smaller inner ring protein |
| PrgH | 392 | AAL21754.1 | MxiG | 371 | ADA76874.1 | YscD | 418 | CAL10061.1 | EscD | 406 | ACG59620.1 | larger inner ring protein | |
| SpaP | 224 | AAL21770.1 | Spa24 | 216 | CAC05828.1 | YscR | 217 | CAL10052.1 | EscR | 217 | ACG59645.1 | export apparatus | |
| SpaR | 263 | AAL21768.1 | Spa29 | 256 | CAC05830.1 | YscT | 261 | CAL10054.1 | EscT | 258 | ACG59643.1 | export apparatus | |
| SpaS | 356 | AAL21767.1 | Spa40 | 342 | ADA76894.1 | YscU | 354 | CAL10055.1 | EscU | 345 | ACG59642.1 | export apparatus, substrate switching | |
| InvA | 685 | AAL21776.1 | MxiA | 686 | AAP79010.1 | YscV | 704 | AAK69216.1 | EscV | 675 | ACG59631.1 | export apparatus | |
| SpaQ | 86 | AAL21769.1 | Spa9 | 86 | ADA76892.1 | YscS | 88 | CAL10053.1 | EscS | 89 | ACG59644.1 | export apparatus | |
| cytoplasm | SpaO | 303 | AAL21771.1 | Spa33 | 293 | ADA76890.1 | YscQ | 307 | CAL10051.1 | EscQ | 305 | ACT74401.1 | sorting platform |
| OrgA | 199 | AAL21750.1 | MxiK | 172 | ADA76878.1 | YscK | 209 | CAL10068.1 | Orf4 | 109 | AAC70125.1 | sorting platform | |
| OrgB | 226 | AAL21749.1 | MxiN | 226 | ADA76879.1 | YscL | 223 | CAL10069.1 | EscL | 204 | ACT74420.1 | sorting platform | |
| InvC | 431 | AAL21774.1 | Spa47 | 430 | ADA76887.1 | YscN | 439 | CAL10048.1 | EscN | 446 | ACG59630.1 | ATPase | |
| indifferent | InvI | 147 | AAL21773.1 | Spa13 | 112 | ADA76888.1 | YscO | 154 | CAL10049.1 | ? | |||
| InvE | 372 | AAL21777.1 | MxiC | 355 | AAP79009.1 | YopN | 293 | CAL10047.1 | SepL | 351 | ACG59619.1 | regulator translocation | |
| InvJ | 336 | AAL21772.1 | Spa32 | 292 | ADA76889.1 | YscP | 453 | CAL10050.1 | Orf16 | 138 | ACT74402.1 | regulator/gatekeeper? | |
| OrgC | 150 | AAL21748.1 | MxiL | 135 | ADA76880.1 | ? | |||||||