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. Author manuscript; available in PMC: 2013 Feb 1.
Published in final edited form as: Neuropharmacology. 2011 Nov 18;62(2):1134–1141. doi: 10.1016/j.neuropharm.2011.11.005

Figure 2.

Figure 2

MALDR-2 mice display MA-induced conditioned place aversion (CPA) at a lower MA dose than MAHDR-2 mice. (A and B) Time in sec/min on the grid floor during a 30-min test for mice previously conditioned with MA on the grid (G+) or on the hole (G−) floor (n = 10–13 per line, group and dose). (C) Percent (%) time on the MA-paired floor by the same animals for the same 30-min test as for the data shown in A and B. Data are collapsed on conditioning group (G+ vs G−) and sex, due to the absence of significant effects of these factors; n = 20–23 per line and dose. Shown are means ± SEM. ***p<.001 for the comparison of G+ and G− at the specific MA dose. **p<.005 for the line comparison at the specific MA dose. MAHDR-2, MA high drinking replicate 2; MALDR-2, MA low drinking replicate 2.