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. 2012 Mar 8;8(3):e1002422. doi: 10.1371/journal.pcbi.1002422

Table 1. Model parameters used for the baseline case.

ID Name Value (Inline graphic) Unit Description
1 Inline graphic Inline graphic none PI activation by bacteria
2 Inline graphic Inline graphic none PI activation by damage
3 Inline graphic Inline graphic none PI inhibition by AI
4 Inline graphic Inline graphic hr PI decay
5 Inline graphic Inline graphic none AI activation by PI
6 Inline graphic Inline graphic none AI activation by Inline graphic
7 Inline graphic Inline graphic hr AI decay
8 Inline graphic 3.22e-06Inline graphic1.17e-06 hr basal neutrophil release from bone marrow reserve
9 Inline graphic Inline graphic none neutrophil release activation by bacteria
10 Inline graphic 3.15e-07Inline graphic1.29e-07 hr maximum neutrophil release from bone marrow reserve in infection
11 Inline graphic Inline graphic hr resting blood neutrophil death
12 Inline graphic Inline graphic cells/ml blood neutrophil priming by bacteria
13 Inline graphic Inline graphic hr blood neutrophil priming
14 Inline graphic Inline graphic none blood neutrophil activation by PI
15 Inline graphic Inline graphic hr blood neutrophil activation
16 Inline graphic Inline graphic hr primed neutrophil death
17 Inline graphic Inline graphic none primed neutrophil activation by PI
18 Inline graphic Inline graphic hr primed neutrophil activation
19 Inline graphic Inline graphic hr neutrophil migration to tissue
20 Inline graphic Inline graphic hr activated blood neutrophil death
21 Inline graphic Inline graphic none activation of neutrophil sequestration by PI
22 Inline graphic Inline graphic hr neutrophil sequestration
23 Inline graphic Inline graphic hr sequestered neutrophil death
24 Inline graphic Inline graphic hr primed neutrophil migration
25 Inline graphic Inline graphic cells/ml activation of neutrophil migration to tissue
26 Inline graphic Inline graphic hr inhibition of neutrophil migration to tissue
27 Inline graphic Inline graphic hr tissue neutrophil death
28 Inline graphic Inline graphic none sequestered neutrophil migration to lung
29 Inline graphic Inline graphic hr lung neutrophil death
30 Inline graphic Inline graphic none damage activation by sequestered neutrophil
31 Inline graphic Inline graphic none damage activation by lung neutrophil
32 Inline graphic Inline graphic hr damage resolution
33 Inline graphic 9.40e+07Inline graphic3.04e+07 numbers/ml/hr Bacteria producing rate by CLP
34 Inline graphic 6.61e-08Inline graphic1.38e-08 ml/neu/hr Rate of bacteria removal by migrated neutrophils

Inline graphic: activation/inhibition constant.

Inline graphic: time constant.