Algorithm 2.
Volumetric lossless registration
V1: Compute 3-D translations between L7 volumes to minimize distance between landmarks |
V2: Compute 3-D elastic warps using drop-3d between V1 volumes |
V3: Using lossless encoding algorithms, apply transformations computed in steps V1 and V2 to L8 volumes to generate aligned artifact mask volumes |
V4: Using lossless encoding algorithms, apply transformations computed in steps V1 and V2 to L9 volumes to output registered cellular gene expression data |