Table 2.
Characteristics of Pertussis-Exposed Healthcare Personnela
| Characteristic | Antibiotic Prophylaxis (N = 42) | Daily Symptom Monitoring Without Prophylaxis (N = 44) | Excluded From Randomization (N = 30) | P Value |
| Age at enrollment in years, median (IQR) | 27 (26–31) | 31 (28–39) | 28 (25–42) | .05 |
| Female | 36 (85.7) | 30 (68.2) | 23 (76.7) | .18 |
| Underlying medical conditionb | 1 (2.4) | 1 (2.3) | 1 (3.3) | 1.00 |
| Occupation | .18 | |||
| Registered nurse | 20 (47.6) | 18 (40.9) | 7 (23.3) | |
| Physician | 11 (26.2) | 19 (43.2) | 10 (33.3) | |
| Respiratory therapist | 2 (4.8) | 3 (6.8) | 5 (16.7) | |
| Radiology technician | 5 (11.9) | 3 (6.8) | 6 (20.0) | |
| Nursing aide | 1 (2.4) | 0 (0.0) | 0 (0.0) | |
| Other | 3 (7.1) | 1 (2.3) | 2 (6.7) | |
| Days from vaccination to exposure, median (IQR) | 429 (263–671) | 336 (216–555) | 405 (281–543) | .44 |
| Days from exposure to acute visit, median (IQR) | 11 (7–13) | 10 (7–13) | … | .56 |
Data are No. (%) of subjects, unless otherwise indicated.
Abbreviation: IQR, interquartile range.
a
Sixteen of 94 healthcare personnel had >1 pertussis exposure and could have contributed data within each column because subjects were randomized following each exposure. Data represents the summary of all exposures.
b
Underlying medical condition includes diabetes mellitus and chronic lung disease. No subjects reported chronic kidney or liver disease, infection with human immunodeficiency virus, hematologic or solid organ malignancy, or taking oral steroids or other immune suppressants.