Table 2.
Tertile of relative telomere length | |||||
---|---|---|---|---|---|
n | RTL mean (std) |
T1 (shortest) OR (95% CI)* |
T2 OR (95% CI)* |
T3 (longest) |
|
Controls n (%) | 947 | 0.77 (0.51) | 314 (33) | 305 (32) | 328 (35) |
Cases n (%) | 911 | 0.75 (0.40) | 319 (35) | 275 (30) | 317 (35) |
Overall | 1.01 (0.80, 1.28) | 0.95 (0.75, 1.20) | 1.00 | ||
Serous | 482 | 0.73 (0.37) | 1.05 (0.79, 1.39) | 0.94 (0.71, 1.25) | 1.00 |
Mucinous | 120 | 0.79 (0.39) | 0.77 (0.46, 1.32) | 1.41 (0.89, 2.24) | 1.00 |
Endometrioid | 132 | 0.77 (0.46) | 0.88 (0.55, 1.42) | 0.89 (0.55, 1.43) | 1.00 |
Clear Cell | 121 | 0.72 (0.41) | 1.07 (0.66, 1.74) | 0.84 (0.51, 1.39) | 1.00 |
Odds ratios and 95% confidence intervals are age adjusted age, study center, study, oral contraceptive use (< 3 mo, 3 mo - 2yrs, 2-5yrs, >5yrs), parity (0,1,2,3,4+), tubal ligation, BMI (<21.9, 22-24.6, 25.7-28.3, >28.3), smoking (never, past, current), family history of breast or ovarian cancer, and race