Table 4.

Reviewed data simulated with mono-exponential analysis

Reviewed data						Simulated on our data
Ref.	n	b-values (s/mm2)	#regions	ADC (range)	P value	b-values (s/mm2)	ADC (range)	P value
Nasu et al. [25]	30	0, 500	2	1.98–2.69	<0.001	0, 500	1.64–2.39	<0.001
Yoshikawa et al. [30]	45	0, 600	4	1.55–1.63	<0.05†	0, 750	1.38–1.91	<0.001
Kiliçkesmez et al. [26]	50	0, 500 ,600	4	1.34–1.77	<0.01	0, 500, 750	1.42–1.98	<0.001
Bruegel et al. [21]	90	50, 300, 600	4	1.12–1.44	<0.001	50, 250, 750	1.02–1.41	<0.001
Mürtz et al. [19]	36	50, 300, 700, 1000, 1300	3	1.00–1.16	<0.05†	50, 250, 750, 1000	0.94–1.10 (only RL)a	0.001

ADCs are means in units of 10⁻³ mm²/s. P values (one-way ANOVA) indicate the significance of differences between different regions in the liver. ^† P value was not mentioned; however the significance level was 5%. ^aMürtz et al. [19] did not evaluate regions in the left lobe; therefore we excluded ROI 3 (left lobe) from the simulation