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BRCA1/2 carrier probability thresholds and corresponding sensitivity and specificity
| Threshold, % | Sensitivity, % (95% CI) | Specificity, % (95% CI) |
|---|---|---|
| ≥ 4 | 98.3 (91.1–100.0) | 34.0 (27.5–41.0) |
| ≥ 5 | 95.0 (86.1–99.0) | 40.9 (34.1–48.0) |
| ≥ 10 | 88.3 (77.4–95.2) | 62.6 (55.5–69.2) |
| ≥ 15 | 81.7 (69.6–90.5) | 72.4 (65.7–78.4) |
