Table 1.

Sensitivity analysis under different censoring mechanisms

		Placebo	Candesartan	p value	Z	Z
		I48 (95% CR)	I48 (95% CR)	(48 months)	mean (SD)	p value
c = 0
1a	l0 = 1, l1 = 1	60.8 (55.1–66.4)	50.9 (45.3–56.6)	0.015	0.296 (0.049)	< 0.0001
2a	l0 = 1.2, l1 = 1	62.1 (56.3–67.7)	50.9 (45.4–56.6)	0.007	0.309 (0.050)	< 0.0001
3a	l0 = 1, l1 = 1.2	60.8 (55.1–64.4)	52.2 (46.5–57.8)	0.034	0.288 (0.049)	< 0.0001
4a	l0 = 1.2, l1 = 0.8	62.0 (56.3–67.7)	49.6 (44.1–55.2)	0.002	0.317 (0.049)	< 0.0001
5a	l0 = 0.8, l1 = 1.2	59.4 (53.8–65.0)	52.2 (46.5–57.8)	0.074	0.273 (0.048)	< 0.0001
6a	l0 = 1, ${\stackrel{-}{l}}_1=$ 1.32	60.8 (55.2–66.4)	52.8 (47.2–58.4)	0.05	0.283 (0.049)	< 0.0001
7a	${\stackrel{-}{l}}_0=0.72,l_1=$ 1	58.8 (53.3–64.3)	50.9 (45.4–56.6)	0.05	0.275 (0.048)	< 0.0001
c = 0.5
1b	l0 = 1, l1 = 1	60.7 (55.0–66.3)	50.8 (45.2–56.5)	0.016	0.295 (0.049)	< 0.0001
2b	l0 = 1.2, l1 = 1	61.9 (56.1–67.6)	50.8 (45.2–56.5)	0.007	0.308 (0.050)	< 0.0001
3b	l0 = 1, l1 = 1.2	60.7 (55.0–66.4)	52.0 (46.3–57.7)	0.034	0.288 (0.049)	< 0.0001
4b	l0 = 1.2, l1 = 0.8	61.9 (56.2–67.6)	49.5 (44.0–55.1)	0.002	0.316 (0.050)	< 0.0001
5b	l0 = 0.8, l1 = 1.2	59.3 (53.7–64.9)	52.0 (46.3–57.7)	0.017	0.273 (0.049)	< 0.0001
6b	l0 = 1, ${\stackrel{-}{l}}_1=$ 1.32	60.7 (55.0–66.3)	52.7 (46.9–58.3)	0.05	0.283 (0.050)	< 0.0001
7b	${\stackrel{-}{l}}_0=0.73,l_1$ = 1	58.8 (53.2–64.4)	50.8 (45.2–56.6)	0.05	0.275 (0.048)	< 0.0001
c = 1.0
1c	l0 = 1, l1 = 1	60.5 (54.8–66.2)	50.6 (44.9–56.3)	0.016	0.294 (0.049)	< 0.0001
2c	l0 = 1.2, l1 = 1	61.7 (55.9–67.4)	50.6 (45.0–56.3)	0.008	0.307 (0.050)	< 0.0001
3c	l0 = 1, l1 = 1.2	60.5 (54.8–66.2)	51.7 (46.0–57.4)	0.033	0.287 (0.050)	< 0.0001
4c	l0 = 1.2, l1 = 0.8	61.7 (55.9–67.4)	49.6 (44.1–55.2)	0.002	0.317(0.049)	< 0.0001
5c	l0 = 0.8, l1 = 1.2	59.2 (53.5–64.8)	51.7 (46.0–57.4)	0.068	0.274 (0.048)	< 0.0001
6c	l0 = 1, ${\stackrel{-}{l}}_1=$ 1.32	60.5 (54.7–66.2)	52.3 (46.6–58.1)	0.05	0.283 (0.050)	< 0.0001
7c	${\stackrel{-}{l}}_0=0.72,l_1=$ 1	58.6 (53.0–64.2)	50.6 (44.9–56.3)	0.05	0.274 (0.048)	< 0.0001