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Measurement of siRNA accumulation into Huh-7 cells by entrapping different amount of siRNA into siRNA nanosomes.
| siRNA concentration | siRNA accumulation into Huh-7 cells
|
|
|---|---|---|
| Percentage of cells | Mean intensity (×1000) | |
| 0 nM | 0.0 | 0.0 |
| 0.74 nM | 24.4±6.0 | 0.44±0.008 |
| 3.7 nM | 93.8±4.0 | 0.94±0.07 |
| 7.4 nM | 99.4±0.05 | 1.96±0.10 |
| 37.0 nM | 100.0±0.0 | 5.87±0.24 |
| 74.0 nM | 100.0±0.0 | 11.82±0.13 |
| 148.0 nM | 100.0±0.0 | 17.94±0.36 |
| 222.0 nM | 99.86±0.15 | 20.73±1.20 |
