Figure - PMC

Skip to main content

View full-text article in PMC

. Author manuscript; available in PMC: 2013 Feb 28.

Published in final edited form as: Int J Pharm. 2011 Dec 6;423(2):525–534. doi: 10.1016/j.ijpharm.2011.11.040

Fig. 3 — Qualitative and quantitative assessment of the inhibition of HCV replication by different siRNA nanosomes at different time points. The HCV (+) replicon cells were cultured in 6-well plates for 24 hours followed by transfection with different formulations, or with IFN for 48 hours. The cells were scraped and re-cultured for 72 hours before they were transfected for a second time with the same formulations, or with IFN for 48 hours. A. Fluorescence photographs of GFP expression using a fluorescence microscope at 10X magnification and B. Quantitative measurement of GFP expression by FACS analysis. The results represent mean ± standard deviation (n=3).

Fig. 3 — Qualitative and quantitative assessment of the inhibition of HCV replication by different siRNA nanosomes at different time points. The HCV (+) replicon cells were cultured in 6-well plates for 24 hours followed by transfection with different formulations, or with IFN for 48 hours. The cells were scraped and re-cultured for 72 hours before they were transfected for a second time with the same formulations, or with IFN for 48 hours. A. Fluorescence photographs of GFP expression using a fluorescence microscope at 10X magnification and B. Quantitative measurement of GFP expression by FACS analysis. The results represent mean ± standard deviation (n=3).