Table 2.
Measurement of particle size (70th percentile) and zeta potential at different time periods (n=4)
| Samples | Day 1 | Month 1 | Month 2 | Month 3 | ||||
|---|---|---|---|---|---|---|---|---|
| Particle size (nm) | Zeta potential (mV) | Particle size (nm) | Zeta potential (mV) | Particle size (nm) | Zeta potential (mV) | Particle size (nm) | Zeta potential (mV) | |
| Liquid liposome | 134±5 | 56±3 | 150±6 | 47±2 | 170±26 | 36±3 | 179±31 | 16±2 |
| Lyophilized liposome powder | 118±3 | 40±6 | 114±5 | 30±10 | 127±11 | 29±4 | 123±18 | 11±3 |
| siRNA nanosome | 642±25 | 48±4 | 572±49 | 30±3 | 435±35 | 19±2 | 413±128 | 17±1 |