TABLE 3.
Main results from this study and previous publications on the diagnosis of erythroderma with skin biopsy
| Feature | Zip and al, 1993 (29) | Walsh and al, 1994 (32) | Trotter and al, 1997 (28) | current study |
|---|---|---|---|---|
| Histopathological diagnosis of underlying cause | 66% | 53% | NA | 73% |
| Correct diagnosis of CTCL | 50% | 60% | 61% | 61% |
| Epidermotropism in CTCL | 50% | NA | NA | 78% |
| Pautrier’s microabcesses in CTCL | NA | NA | 20% | 44% |
| Moderate to high density of infiltrate in CTCL | 75% | NA | NA | 95% |
| Epidermal hyperplasia in CTCL | 50% | NA | 35% | 50% |
| Neutrophils in dermal infiltrate in psoriasis | 69% | NA | NA | 33% |
| Superficial perivascular infiltrate in psoriasis | 100% | NA | NA | 44% |
| Epidermal hyperplasia in psoriasis | 94% | NA | NA | 66% |
| Dilated blood vessels in papillary dermis of psoriasis | 81% | NA | NA | 89% |
| Suprapapillary thinning in psoriasis | 69% | NA | NA | 22% |
| Exocytosis of neutrophils in psoriasis | 63% | NA | NA | 78% |
| Spongiosis in eczema | 79% | NA | NA | 80% |
| Epidermal hyperplasia in eczema | 71% | NA | NA | 100% |
| Superficial perivascular infiltrate in eczema | 86% | NA | NA | 80% |
| Moderate to high density of infiltrate in eczema | 71% | NA | NA | 60% |
| Moderate to high density of infiltrate in drug-induced erythroderma | 83% | NA | NA | 20% |
| Epidermal hyperplasia in drug-induced erythroderma | 33% | NA | NA | 80% |
CTCL, cutaneous T cell lymphoma; NA, not available