Table 2.
Type | Description |
---|---|
Benchmarking 1 | Conservative approach choosing the most resistant, persistent, and robust surrogate without exptl access to the organism |
Benchmarking 2 | Through a literature review, demonstrating that the surrogate possesses the same exptl attributes as the target pathogen without access to the organism |
Benchmarking 3 | Demonstrating and documenting the range of surrogate behaviors with confidence limits and then placing the target pathogens in the appropriate range on a full spectrum; does not require access to the target pathogen |
Validation | Experimentally comparing the surrogate and the target pathogen under the same conditions in the same laboratory |