Table 4. Levels of cytokines in CNV and control group (mean±SD).
Cytokines | <3 mon | >3 mon | Control | P* | Exudative AMD | PM | Idiopathic CNV | p* |
---|---|---|---|---|---|---|---|---|
IL-1b |
1.98±0.28 |
1.99±0.23 |
1.94±0.20 |
0.672 |
2.1±0.3 |
1.9±0.2 |
2.0±0.2 |
0.287 |
IL-6 |
3.94±2.37 |
4.49±3.09 |
4.47±2.07 |
0.610 |
3.6±1.8 |
4.9±2.0 |
3.1±1.5 |
0.124 |
IL-8 |
4.18±1.22 |
5.52±2.59 |
5.51±2.90 |
0.118 |
4.5±1.5 |
4.9±0.8 |
4.3±1.0 |
0.145 |
IL-10 |
1.82±0.23 |
1.85±0.25 |
1.90±0.17 |
0.257 |
1.8±0.3 |
1.9±0.1 |
1.8±0.3 |
0.258 |
IL-12p |
2.08±0.19 |
2.19±0.31 |
2.19±0.27 |
0.444 |
2.2±0.3 |
2.2±0.2 |
2.1±0.3 |
0.755 |
TNF-α | 1.90±0.22 | 1.85±0.27 | 1.95±0.28 | 0.507 | 1.9±0.2 | 1.8±0.2 | 2.0±0.4 | 0.621 |
*Kruskal–Wallis H test was used. CNV, choroidal neovascularization group; <3mon, patients who receive last IVB within 3 months; >3mon, patients who receive last IVB for more than 3 months and never; Control, patients with cataract and idiopathic epiretinal membrane or macular hole who underwent combined cataract and vitrectomy surgery; AMD, age-related macular degeneration; PM, pathological myopia; CNV, choroidal neovascularization; IL, interleukin; TNF, tumor necrosis factor.