Table 2.
Expression of BCA2 and hHR23a in breast cancer cases
| Cytoplasmic BCA2 | Nuclear BCA2 | Cytoplasmic hHR23a | Nuclear hHR23a | |||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Variable | Low (%) | High (%) | P-value | Low (%) | High (%) | P-value | Low (%) | High (%) | P-value | Low (%) | High (%) | P-value | ||||||||
| ER | ||||||||||||||||||||
| Positive | 27 | (34.2) | 52 | (65.8) | 0.8053 | 29 | (36.7) | 50 | (63.3) | 0.4772 | 27 | (34.2) | 52 | (65.8) | *0.0181 | 39 | (50.0) | 39 | (50.0) | 0.4947 |
| Negative | 7 | (29.2) | 17 | (70.8) | 11 | (45.8) | 13 | (54.2) | 2 | (8.3) | 22 | (91.7) | 10 | (41.7) | 14 | (58.3) | ||||
| PR | ||||||||||||||||||||
| Positive | 17 | (31.3) | 39 | (68.7) | 0.6743 | 17 | (30.4) | 39 | (69.6) | 0.0686 | 19 | (33.9) | 37 | (66.1) | 0.1897 | 26 | (47.3) | 29 | (52.7) | 1.000 |
| Negative | 17 | (36.1) | 30 | (63.9) | 23 | (48.9) | 24 | (51.1) | 10 | (21.3) | 37 | (78.7) | 23 | (48.9) | 24 | (51.1) | ||||
| HER2 | ||||||||||||||||||||
| Positive | 6 | (35.3) | 11 | (64.7) | 1.000 | 8 | (47.1) | 9 | (52.9) | 0.5878 | 5 | (29.4) | 12 | (70.6) | 1.000 | 10 | (58.8) | 7 | (41.2) | 0.4292 |
| Negative | 28 | (32.9) | 57 | (67.1) | 32 | (37.6) | 53 | (62.4) | 23 | (27.1) | 62 | (72.9) | 39 | (46.4) | 45 | (53.6) | ||||
| Grade | ||||||||||||||||||||
| 1 | 2 | (22.2) | 7 | (77.8) | 0.5501 | 4 | (44.4) | 5 | (55.6) | * 0.0297 | 3 | (33.3) | 6 | (66.7) | 0.2730 | 5 | (55.6) | 4 | (44.4) | 0.4142 |
| 2 | 18 | (38.3) | 29 | (61.7) | 12 | (25.5) | 35 | (74.5) | 14 | (29.8) | 33 | (70.2) | 19 | (41.3) | 27 | (58.7) | ||||
| 3 | 14 | (30.4) | 32 | (69.6) | 24 | (52.5) | 22 | (47.8) | 12 | (26.1) | 34 | (73.9) | 25 | (54.3) | 21 | (45.7) | ||||
| Nodal | ||||||||||||||||||||
| Positive | 11 | (32.4) | 23 | (67.6) | 1.000 | 10 | (29.4) | 24 | (70.6) | 0.1952 | 14 | (41.2) | 20 | (58.8) | 0.0585 | 17 | (51.5) | 16 | (48.5) | 0.6649 |
| Negative | 20 | (33.3) | 40 | (66.7) | 26 | (43.3) | 34 | (56.7) | 13 | (21.7) | 47 | (78.3) | 27 | (45.0) | 33 | (55.0) | ||||
* Indicates a correlation which is statistically significant by Fisher's exact t-test or χ2 test