Table 1.

Number of patients recruited by treatment group and study

RCT	Location	Reference	ACT				Mono-therapy		non-ACT	Total
			AS&AQ	AL	DP	AS+SP	AQ	AS	AQ+SP
ACT vs monotherapy	Multicentre	[5]	306				307			613
	Rwanda	[17]	158				150			308
	Mali	[13]	252			249		252		753
ACT vs ACT and non-ACT	Uganda	[14]	242	217					269	728
	Rwanda	[15]	252		251				258	761
	Multicentre	[16]	626	311						937
	Zanzibar	[10]	202	200						402
Total			2038	728	251	249	457	252	527	4502