Table 2.
Histomorphometric parameters of trabecular bone from metaphysis of tibiae evaluated by histochemical analysis.
| Parameters | Sham n = 7 |
OVX n = 7 |
1SM n = 7 |
3SM n = 7 |
10SM n = 7 |
30SM n = 7 |
|---|---|---|---|---|---|---|
| BV/TV (%) | 55.44 ± 7.10 | 10.24 ± 3.68 * | 11.51 ± 2.27 | 11.61 ± 2.27 | 15.19 ± 1.61 | 18.70 ± 1.38 # |
| Tb.Th (mcm) | 35.14 ± 5.17 | 14.86 ± 5.54 * | 15.72 ± 3.33 | 16.37 ± 3.03 | 21.32 ± 3.71 | 26.37 ± 2.49 # |
| Tb.N (1/mm) | 15.87 ± 1.59 | 5.73 ± 2.03 * | 6.06 ± 1.99 | 6.39 ± 2.00 | 8.88 ± 2.61 | 12.35 ± 2.67 # |
| Tb.Sp (mcm) | 28.38 ± 5.80 | 199.70 ± 3.48 * | 180.27 ± 3.46 | 176.26 ± 2.18 | 98.75 ± 7.21 | 81.67 ± 6.38 # |
| Oc.N/10 HPF | 5 ± 1.41 | 17 ± 2.40 * | 16 ± 2.39 | 17 ± 2.20 | 13 ± 2.26 | 10 ± 1.41 # |
Note: Results are presented as the means ± SD. *p < 0.001 vs. Sham group; #p < 0.05 vs. OVX group. BV/TV, bone volume fraction; Tb.Th, trabecular thickness; Tb.N, trabecular number; Tb.Sp, trabecular separation; Oc.N, osteoclast number. Rat groups as defined above (N = 7/each group).