Table 1.
Clinical and laboratory finding of the patients in this study
| Patient 1 | Patient 2 | Patient 3 | |
|---|---|---|---|
| Family history available | No | Yes | No |
| Age at the time of the study | 4 years | 21 months | 16 months |
| Age at onset | 3 years | 17 months | 16 month |
| Fever | Yes | Yes | Yes |
| Hepatomegaly | 4 cm | 5 cm | 2.5 cm |
| Splenomegaly | 2 cm | 3 cm | 1 cm |
| White blood cells (×109/L) | 11.6 | 6.36 | 3.03 |
| Neutrophils (×109/L) | 1.61 | 3.915 | 0.56 |
| Hemoglobin (g/dL) | 8.1 | 9.6 | 7.5 |
| Platelets (×109/L) | 95 | 56 | 30 |
| LDH (IU/L) | 449 | 1,693 | 1,698 |
| AST (IU/L) | 88 | 122 | 453 |
| ALT (IU/L) | 31 | 25 | 255 |
| Ferritin (μg/L) | 1,276 | 26,282 | 11,129 |
| sIL-2R (U/mL) | 3,162 | 2,880 | 14,334 |
| IgG (mg/dL) | 1,821 | 806 | 423 |
| IgA (mg/dL) | 302 | 124 | 32 |
| IgM (mg/dL) | 1,843 | 40 | 18 |
| Whole blood EBV-DNA (copies/mL) | 140,000 | 5,700 | 1,400,000 |
LDH, lactate dehydrogenase; AST, aspartate amino transferase; ALT, alanine amino transferase, sIL-2R, soluble interleukin-2 receptor; NA: not available.