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. Author manuscript; available in PMC: 2012 Nov 1.
Published in final edited form as: Nat Chem Biol. 2011 Nov;7(11):803–809. doi: 10.1038/nchembio.663

Figure 1.

Figure 1

Crystal structure of (R)-naproxen within the mCOX-2 active site. (a) Stereoview of (R)-naproxen (green sticks) bound in the COX-2 active. The simulated annealing omit map (Fo-Fc) contoured at 3σ is displayed in the vicinity of (R)-naproxen. Protein residues are shown in cyan sticks. (b) Stereoview of the active site of the (R)-naproxen-COX-2 complex (green sticks) overlaid with the (S)-naproxen-COX-2 complex (grey sticks).

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