Table 1.
Clinical Characteristics of KEEP Participants, 2000-2009, by eGFR Categories Defined Using the CKD-EPI Equation
| CKD-EPI eGFR (mL/min/1.73 m2) |
|||||||
|---|---|---|---|---|---|---|---|
| No. of Participants |
≥120 | 90-119 | 60-89 | 45-59 | 30-44 | <30 | |
| No. (row percent) | 116,321 | 6,827 (5.9) | 42,469 (36.5) | 50,412 (43.3) | 11,261 (9.7) | 4,234 (3.6) | 1,118 (1.0) |
| Age | |||||||
| 18-30 y | 8,263 | 3,214 (47.1) | 3,897 (9.2) | 1,077 (2.1) | 47 (0.4) | 15 (0.4) | 13 (1.2) |
| 31-45 y | 23,165 | 2,656 (38.9) | 13,660 (32.2) | 6,343 (12.6) | 390 (3.5) | 63 (1.5) | 53 (4.7) |
| 46-60 y | 40,633 | 935 (13.7) | 17,945 (42.2) | 18,751 (37.2) | 2,308 (20.5) | 522 (12.3) | 172 (15.4) |
| 61-75 y | 33,156 | 20 (0.3) | 6,678 (15.7) | 18,920 (37.5) | 5,282 (46.9) | 1,837 (43.4) | 419 (37.5) |
| >75 y | 11,104 | 2 (0.0) | 289 (0.7) | 5,321 (10.6) | 3,234 (28.7) | 1,797 (42.4) | 461 (41.2) |
| Sex | |||||||
| Men | 37,160 | 1,446 (21.2) | 13,125 (30.9) | 17,290 (34.3) | 3,592 (31.9) | 1,283 (30.3) | 424 (37.9) |
| Women | 79,161 | 5,381 (78.8) | 29,344 (69.1) | 33,122 (65.7) | 7,669 (68.1) | 2,951 (69.7) | 694 (62.1) |
| Race | |||||||
| White | 57,355 | 1,323 (19.4) | 17,677 (41.6) | 27,813 (55.2) | 7,130 (63.3) | 2,770 (65.4) | 642 (57.4) |
| African American | 38,521 | 4,080 (59.8) | 14,886 (35.1) | 15,378 (30.5) | 2,878 (25.6) | 999 (23.6) | 300 (26.8) |
| Other | 20,445 | 1,424 (20.9) | 9,906 (23.3) | 7,221 (14.3) | 1,253 (11.1) | 465 (11.0) | 176 (15.7) |
| Self-reported conditionsa | |||||||
| Diabetes | 34,283 | 1,151 (17.0) | 11,017 (26.1) | 15,187 (30.3) | 4,341 (38.7) | 2,015 (47.7) | 572 (51.4) |
| Hypertension | 65,340 | 1,937 (28.6) | 19,187 (45.6) | 30,699 (61.3) | 8,773 (78.4) | 3,719 (88.3) | 1,025 (92.1) |
| Coronary artery disease | 10,104 | 155 (2.3) | 2,075 (4.9) | 4,766 (9.5) | 1,855 (16.5) | 972 (23.0) | 281 (25.1) |
| Congestive heart failure | 2455 | 60 (1.6) | 571 (2.3) | 1,088 (3.5) | 396 (5.8) | 245 (9.6) | 95 (14.9) |
| Cerebrovascular disease | 5,643 | 125 (1.9) | 1,294 (3.2) | 2,655 (5.6) | 903 (8.5) | 500 (12.6) | 166 (15.7) |
| Peripheral vascular disease | 4,644 | 185 (2.7) | 1,389 (3.3) | 2,005 (4.0) | 629 (5.6) | 318 (7.5) | 118 (10.6) |
| WHO anemiab | 13,839 | 1,245 (18.6) | 4,153 (9.9) | 4,620 (9.3) | 1,820 (16.4) | 1,350 (32.4) | 651 (59.5) |
Note: Values are number (column percent) unless otherwise indicated. Conversion factor for eGFR in mL/min/1.73 m2 to mL/s/1.73 m2, ×0.01667.
Abbreviations: CKD-EPI, Chronic Kidney Disease Epidemiology Collaboration; eGFR, estimated glomerular filtration rate; KEEP, Kidney Early Evaluation Program; WHO, World Health Organization.
Diabetes includes self-reported diabetes and using medication; hypertension includes self-reported hypertension and using medication; coronary artery disease includes history of heart attack, coronary artery bypass graft, angioplasty, and coronary artery disease; congestive heart failure data available starting 2005; cerebrovascular disease is defined as stroke; peripheral vascular disease includes peripheral vascular disease for 2000-2004 and limb amputation for 2005-2009.
Defined as hemoglobin level <13 g/dL for men and <12 g/dL for women.