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. Author manuscript; available in PMC: 2012 Dec 1.
Published in final edited form as: Clin Ther. 2011 Dec;33(12):B16–B39. doi: 10.1016/j.clinthera.2011.11.016

Table 2. Suggested Presentation of Range of Response and of Remission Rates in Clinical Trials 17, 20, 21.

Presentation of Responder and Remission Rates based on Percentage Change on the Positive and Negative Syndrome Scale (PANSS)12 or the Brief Psychiatric Rating Scale (BPRS)11
Criteria Total n ≤0% PANSS/BPRS reduction >0% - 24% PANSS/BPRS reduction 25% - 49% PANSS/BPRS reduction 50% - 74% PANSS/BPRS reduction 75% - 100% PANSS/BPRS reduction Remission*
Intervention Group N n (%) n (%) n (%) n (%) n (%) n (%)
Control Group N n (%) n (%) n (%) n (%) n (%) n (%)
Presentation of Responder and Remission Rates based on Clinical Global Impressions (CGI) Improvement and Severity Scores13
CGI-improvement score Total n Very much worse Much worse Minimally worse unchanged Minimally improved Much improved Very much improved
Score 7 6 5 4 3 2 1
Intervention Group N n (%) n (%) n (%) n (%) n (%) n (%) n (%)
Control Group N n (%) n (%) n (%) n (%) n (%) n (%) n (%)
CGI-severity score Total n Extremely ill Severely ill Markedly ill Moderately ill Mildly ill Borderline mentally ill Normal, not at all ill
Score 7 6 5 4 3 2 1
Intervention Group N n (%) n (%) n (%) n (%) n (%) n (%) n (%)
Control Group N n (%) n (%) n (%) n (%) n (%) n (%) n (%)

Modified from: Leucht et al. 2007 21; Leucht & Kane 2006 17;

*

based on Andreasen et al 2005 20