Table 2.
Multivariate analysis of PALN recurrence
| Parameters | Number | Hazard ratio (95% CI) | p value |
|---|---|---|---|
| Age | 0.233 | ||
| < 50 | 58 | reference | |
| 50-60 | 59 | -- | 0.124 |
| > 60 | 71 | -- | 0.141 |
| Stage | 0.831 | ||
| I | 22 | reference | |
| II | 145 | -- | 0.852 |
| III-IVA | 41 | -- | 0.686 |
| Parametrial score | 0.056 | ||
| 0 | 36 | reference | |
| 1-3 | 103 | -- | 0.749 |
| 4-6 | 49 | -- | 0.222 |
| Tumor size (cm) | 0.333 | ||
| ≤ 5.0 | 48 | reference | |
| > 5.0 | 53 | 0.304 | |
| unknown | 87 | 0.836 | |
| Positive pelvic node | -- | 0.170 | |
| Hemoglobin < 12 g/dL | -- | 0.525 | |
| Smoking | -- | 0.484 | |
| Field size (< 18 cm) | -- | 0.959 | |
| Pretreatment CEA level (ng/mL) | 0.005 | ||
| < 5 | 149 | reference | |
| 5-10 | 16 | 1.007 (0.232-4.365) | 0.993 |
| ≥ 10 | 23 | 4.206 (1.801-9.821) | 0.001 |
| Pretreatment SCC-Ag level (ng/mL) | < 0.001 | ||
| < 10 | 128 | reference | |
| 10-40 | 42 | 2.617 (1.180-5.804) | 0.018 |
| ≥ 40 | 18 | 6.851 (2.722-16.935) | < 0.001 |
Abbreviations: CI = confidence interval; SCC-Ag = squamous cell carcinoma antigen; CEA = Carcinoembryonic antigen