Figure 5.

Secretion of the Th1 cytokines IL-12 and IFN-γ in PRRSV infected pigs. Plasma samples collected from pigs on day 0 pre-infection (n = 50) and day 2 post-infection of infected (n = 25) and contact (n = 25) pigs were analyzed by ELISA to determine cytokine levels: (A and C) IL-12; (B and D) IFN-γ secreted by indicated pig groups at day 0 and day 2 post-infection. Each bar represents the amount of cytokines secreted by individual pigs, and numbers shown above the horizontal lines indicate the average amount of cytokine from 25 pigs +/- standard deviation. Statistical analysis was performed using a paired t-test by comparing day 0 and day 2 cytokine responses.