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. 2012 Feb 28;16(1):65–70. doi: 10.4196/kjpp.2012.16.1.65

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Copyright © 2012 The Korean Physiological Society and The Korean Society of Pharmacology

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Fig. 1 — Switching effect of 5-HT on the induction of LTP in the rat visual cortex. (A) The effect of the TBS of layer 4 (indicated with arrow) on layer 2/3 FP in control slices (open circle, n=10) and in 5-HT-perfused slices (closed circle, n=10) from 5-week-old rats. The right panel shows the representative average traces in a slice marked with corresponding symbols, which were taken at the time period indicated with corresponding numbers. Scales represent 0.4 mV and 2 ms, respectively. (B) The effect of the TBS of layer 4 (indicated with arrow) on layer 2/3 FP in control slices (open circle, n=11) and in 5-HT-perfused slices (closed circle, n=12) from 8-week-old rats. The right panel shows the representative average traces in a slice marked with corresponding symbols, which were taken at the time period indicated with corresponding numbers. Scales represent 0.4 mV and 2 ms, respectively. (C) Age-dependent inhibition and facilitation of layer 2/3 LTP induction induced by TBS to layer 4 in the rat visual cortex. Numbers of the experiments are from 5 to 12. ^**p<0.01 and ^***p<0.001 compared with the corresponding control.