Table 1.
Average ZNF804A cDNA allele ratios at rs12476147 in 10 brain regions from eight subjects
| Subject no. | DLPFC | OCC | TEMP | PAR | AMYG | HIPP | CER | NAC | CAUD | SN | P |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 1.00 (0.06) | 0.99 (0.09) | 0.86 (0.08) | 1.17 (0.22) | 1.71 (0.45) | 1.15 (0.05) | 1.30 (0.21) | 1.15 (0.05) | 1.15 (0.05) | 0.0032 | |
| 5 | 0.91 (0.17) | 0.89 (0.08) | 1.01 (0.03) | 1.01 (0.09) | 1.21 (0.10) | 1.05 (0.11) | 1.02 (0.09) | 1.35 (0.19) | 1.21 (0.14) | 0.88 (0.26) | 0.0031 |
| 10 | 0.98 (0.05) | 1.07 (0.04) | 0.99 (0.16) | 1.00 (0.09) | 1.14 (0.15) | 1.06 (0.13) | 0.81 (0.15) | 1.03 (0.09) | 1.19 (0.13) | 0.93 (0.33) | 0.058 |
| 15 | 1.09 (0.18) | 1.19 (0.28) | 1.12 (0.11) | 1.32 (0.33) | 1.17 (0.39) | 1.28 (0.16) | 1.07 (0.08) | 1.04 (0.11) | 0.605 | ||
| 22 | 1.01 (0.12) | 0.88 (0.05) | 1.01 (0.06) | 0.97 (0.06) | 1.06 (0.04) | 0.97 (0.05) | 0.044 | ||||
| 24 | 1.03 (0.03) | 1.07 (0.10) | 1.08 (0.03) | 1.08 (0.05) | 1.13 (0.06) | 1.34 (0.04) | 1.03 (0.08) | 0.021 | |||
| 30 | 1.00 (0.06) | 1.15 (0.13) | 1.19 (0.02) | 1.11 (0.07) | 1.24 (0.10) | 0.90 (0.06) | 0.0053 | ||||
| 34 | 1.18 (0.07) | 1.09 (0.03) | 1.13 (0.05) | 1.09 (0.04) | 1.22 (0.04) | 1.03 (0.05) | 1.15 (0.07) | 1.13 (0.05) | 1.02 (0.11) | 0.0096 |
Ratios are the average of four measures of each sample, corrected by the average allele ratio derived from concurrent assay of heterozygous genomic DNA. Standard deviations are shown in parentheses. Blank cells correspond to samples that were unavailable for assay. P-values are given for Kruskal–Wallis tests of differences in allelic expression across all assayed brain regions for each subject. P-values in bold are those that survived Bonferroni correction for eight tests.
DLPFC, dorsolateral prefrontal cortex; OCC, occipital cortex; TEMP, temporal cortex; PAR, parietal cortex; AMYG, amygdala; HIPP, hippocampus; CER, cerebellum; NAC, nucleus accumbens; CAUD, caudate; SN, substantia nigra.