Table 1.

Morphometric analysis of synaptic ultrastructure in the stratum radiatum of the hippocampal CA1 region

	P10		P23		P90
	WT	KO	WT	KO	WT	KO
No. of mice analyzed	3	3	3	3	4	4
No. of synapses analyzed	241	272	281	246	342	357
Synapses area (μm2)	0.239 ± 0.009	0.234 ± 0.007	0.141 ± 0.005	0.128 ± 0.002	0.192 ± 0.007	0.201 ± 0.007
AZ length (μm)	0.219 ± 0.005	0.210 ± 0.005	0.182 ± 0.005	0.162 ± 0.004	0.174 ± 0.003	0.175 ± 0.003
SV density (SV/μm2)	97 ± 3.18	79 ± 3.23	183 ± 4.8	105 ± 4.3	332 ± 6.4	164 ± 4.4**

Statistical analysis was performed using the unpaired Student’s t-test KO versus WT. **P < 0.01.